NexGard Spectra is suitable for use with dogs and puppies from 8 weeks of age, with a minimum body weight of 4.5 lbs (2 kg). 95% of Bush ticks were killed by 72 hours. It is recommended, in accordance with the American Heartworm Society that: - Infected dogs should be treated with labeled adulticides and microfilaricides (if microfilaria are present) as soon after diagnosis as medically practical. Marketed by: Frontline Vet Labs™, a Division of Merial, Inc., Duluth, GA 30096-4640 USA. This dog experienced a third seizure one week after receiving the third dose. HOW SUPPLIED: NEXGARD SPECTRA Chewable Tablets are available in five soft, beef-flavoured chewable tablets strengths packaged in blister packs: 9.4/1.9 mg, 18.8/3.8 mg, 37.5/7.5 mg, 75.0/15.0 mg or 150.0/30.0 mg of Afoxolaner/Milbemycin Oxime per chewable tablet, formulated according to the weight of dogs. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. Treatment may begin at any time of the year, and should continue the entire year without interruption. One of the dogs in the NEXGARD SPECTRA group with a Clostridium perfringens infection died suddenly. Treatment may begin at any time of the year, and should continue the entire year without interruption. In a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. Discount Pet Medications => : Flea & Tick :: For Dogs : Start => : Flea & Tick :: For Dogs : NexGard for Dogs - 60 - 120 lbs - RED - 3 tablets. Ne pas utiliser en cas d’hypersensibilité aux substances actives ou à l’un des excipients. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Remove only one chewable at a time from the foil-backed blister card. (see EFFICACY). Nexgard Spectra est utilisé dans le traitement des infestations par les puces et les tiques et/ou des vers intestinaux chez les chiens. Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. Nexgard spectra chien 4 10 kg. NexGard Spectra demonstrated that within 48 hours of dosing 95% of Paralysis and Brown Dog ticks were killed. NexGard Spectra est administré une fois par mois à croquer, avec la dose exacte en fonction du poids corporel de votre chien. Is he going to be OK, or do I need to take him to an emergency vet? This site is provided as an information service for veterinary professionals. Clinical observations included diarrhea, diarrhea with blood and vomiting which were observed sporadically across all groups, including the controls. - the treatment and control of intestinal nematode infections caused by adult hookworms (Ancylostoma caninum), adult roundworms (Toxocara canis and Toxascaris leonina) and adult whipworms (Trichuris vulpis). At subsequent infestations, every week between 7 and 35 days after treatment, fleas from dogs in the treated group were unable to produce any eggs while fleas from dogs in the control group continued to produce eggs (means 8.9-82.3). La dose recommandée doit ê tre strictement respectée chez les colleys ou les races apparentées. It is not believed these adverse reactions were treatment-related. NexGard SPECTRA is a highly palatable chew that is readily consumed by dogs when offered as a treat. NexGard kills 3 common types of ticks (the American dog tick, the black-legged ?Deer? These reactions are presumably caused by the release of protein from dead or dying microfilariae. NexGard Spectra has not been evaluated as safe for use on pregnant or lactating dogs. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. Nexgard Spectra e n’a entraîné aucun effet indésirable grave. Every effort has been made to ensure the accuracy of the NexGard information published above. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. If it is suspected that any of the dose has been lost, or vomiting occurs within 2 hours of administration, redose with another full dose. Reported Adverse Reactions during the 6 month study, 1Number of dogs treated with the identified adverse reaction. Is NexGard Spectra water fast? Intestinal Nematodes: In well-controlled laboratory studies, NEXGARD SPECTRA demonstrated > 90% effectiveness against adult hookworms (Ancylostoma caninum), adult roundworms (Toxocara canis and Toxascaris leonina) and adult whipworms (Trichuris vulpis). Dogs over 60kg (132 pounds ) manage the Proper mix of entire chewables. Dosage. Nexgard Spectra is a tasty beef-ﬂavoured chew that dogs love, making it easy to give, with or without food. See product label for full claim details and usage instructions. For ease of dosing, NexGard SPECTRA can be given with or without food. In two well-controlled laboratory studies, NEXGARD SPECTRA was 69% effective against heartworm infections induced with the US JYD-34 strain when administered for 6 consecutive monthly doses. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. To be effective NEXGARD SPECTRAs… Afoxolaner is a member of the isoxazoline family, shown to bind at a binding site to inhibit insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. NexGard is for use in dogs only. For prevention of flea infestation, NEXGARD SPECTRA should be administered ideally just before fleas become active. Such dogs may be susceptible to macrocyclic lactone toxicity with over-dosing or when used in combination with other macrocyclic lactone drugs. It gives protection against fleas for up to five weeks and controls ticks for up to four weeks. NexGard (afoxolaner) is for use in dogs only. 2 – 3,5 . Nb et dosage de comprimé de Nexgard Spectra . Administration of NEXGARD SPECTRA should coincide with the time of year the ticks are active. I'm sure the Veterinarian can help you. 38/8mg . tick and the Lone Star tick). Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or rejected. According to Drugs.com, dogs showed no ill effects, even when given a dosage 80 times higher than the amount in Denamarin for a period of 26 weeks. Nexgard/Nexgard Spectra. In case of accidental ingestion, contact a physician immediately. Recommended Dosage Note: It’s important to speak to the vet before giving NexGard to your dog. In the clinical field study there were 2 dogs in the NEXGARD SPECTRA group and one dog in the active control group that had diarrhea associated with Clostridium perfringens infection. NEXGARD SPECTRA should be administered at monthly intervals beginning within 1 month of the dog’s first exposure to mosquitoes and continuing for 6 months after the dog’s last exposure to mosquitoes (see EFFICACY). Dogs over 60kg (132 pounds ) manage the Proper mix of entire chewables. - the treatment and control of Dermacentor variabilis (American Dog Ticks), Ixodes scapularis (Blacklegged Ticks), and Amblyomma americanum (Lone Star Ticks). All NexGard SPECTRA. The selective toxicity of Afoxolaner between insects/acarines and mammals may be inferred by the differential sensitivity of the insects/acarines’ GABA receptors versus mammalian GABA receptors. - Annual testing of all dogs for heartworm should be done. On Day 28, NexGard was 81.1% effective 12 hours post-infestation. NexGard Spectra is a monthly chewable treatment for dogs made with soy proteins and braised beef flavorings that dogs love. Administer the appropriate combination of chewables. Once feeding begins for fleas (C. felis), the onset of effect is within 8-24 hours. VCA Animal Hospitals states that mild digestive upset may occur in dogs taking milk thistle, the herb containing silybin. If treatment is delayed, whether by a few days or many, immediate treatment with NEXGARD SPECTRA and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms. Treatment with NexGard may begin at any time of the year (see Effectiveness). NEXGARD SPECTRA is not 100% effective for the prevention of all strains of heartworm. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. DIN 02473364 (9.4 mg/1.9 mg), 02473372 (18.8 mg/3.8 mg), 02473380 (37.5 mg/7.5 mg), 02473399 (75 mg/15 mg), 02473402 (150 mg/30 mg), Boehringer Ingelheim Animal Health Canada Inc., 5180 South Service Road, Burlington ON L7L 5H4. NexGard Spectra for X-Small Dogs - 4 - 8 lbs - ORANGE - 3 tablets. Intestinal Nematodes Treatment and Prevention: Dogs may be exposed to and can become infected with hookworms, roundworms and whipworms throughout the year. Clostridium perfringens infection and gastritis with hypomotility were detected and were not determined to be treatment-related. NexGard Spectra Chewable Tablets for Dogs. The most frequently reported adverse reaction in the NEXGARD SPECTRA and active control groups was vomiting. Skin scrapings from dogs presenting signs suggestive of sarcoptic mange were examined to confirm infestation. NexGard Spectra Chewable Tablets are chewable beef flavoured tablets for dogs used for the treatment of flea and tick infestations as well as the prevention of heartworm disease and treatment of … NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. In a well-controlled US field study in client owned dogs, which evaluated safety and effectiveness against Dirofilaria immitis in a total of 315 treated dogs (160 treated with NEXGARD SPECTRA, 155 treated with an oral active control; all dogs were administered one dose at monthly intervals for six consecutive administrations). Nous avons souvent entendu des gens nous dirent, nous on ne donne pas Bravecto , trop de risques, mon vétérinaire le déconseille, or le Nexgard contient de l'afoxolaner et cette substance fait partie de la famille des isoxazolines, tout comme pour le Bravecto. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using these data. NexGard can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. - the reduction of Borrelia burgdorferi infections as a direct result of killing adult Ixodes scapularis vector ticks. Both NexGard® and NexGard Spectra® are now approved for the treatment of the cutaneous diseases demodicosis (caused by the Demodex canis mite) as well as sarcoptic mange (caused by the Sarcoptes scabiei var. Should your dog vomit within 2 hours of the dose having been administered, then redose again giving another full dose. Dosage Schedule. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: NEXGARD SPECTRA is a soft, beef-flavored chewable tablet. Afoxolaner is a member of the isoxazoline class. Dogs in the control group were sham-dosed. 19/4mg . The new soft, beef flavored chew kills fleas and ticks, now with the added benefit of treatment for heartworms, roundworms, hookworms, and whipworms. Not all adverse events are reported to FDA/CVM. Strange behavior is often perplexing. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or rejected. If a dose is missed, administer NexGard and resume a monthly dosing schedule. A third dog with a history of seizures received NexGard and experienced no seizures throughout the study. Prolonged Afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. Copyright © 2021 Animalytix LLC. NexGard peut être pris en même temps que Heardgard Plus pour la protection complète contre le ver du cœur et les parasites internes. Collectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations. 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